Article
Neuronal differentiation rescued by implantation of Weaver granule cell precursors into wild-type cerebellar cortex.
Science (New York, N.Y.) - 16 Apr 1993
Gao W Q, Hatten M E
Abstract excerpt
The migration of postmitotic neurons away from compact, germinal zones is a critical step in neuronal differentiation in the developing brain. To study the molecular signals necessary for cerebellar granule cell migration in situ, precursor cells from the neurological mutant mouse weaver, an animal with phenotypic defects in migration, were implanted into the external germinal layer (EGL) of wild-type cerebellar...
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