Neuronal differentiation rescued by implantation of Weaver granule cell precursors into wild-type cerebellar cortex.

doi:10.1126/science.8469990

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Article

Neuronal differentiation rescued by implantation of Weaver granule cell precursors into wild-type cerebellar cortex.

Science (New York, N.Y.) - 16 Apr 1993

Gao W Q, Hatten M E

Abstract excerpt

The migration of postmitotic neurons away from compact, germinal zones is a critical step in neuronal differentiation in the developing brain. To study the molecular signals necessary for cerebellar granule cell migration in situ, precursor cells from the neurological mutant mouse weaver, an anim...

Topics

Animals
Cell Differentiation
Cell Movement
Cerebellar Cortex
Genes
Mice
Mice, Neurologic Mutants
Microscopy, Fluorescence
Models, Neurological
Neurons
Phenotype
Stem Cell Transplantation
Stem Cells

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