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Article

Statin Targeted Treatment Against Intimal Hyperplasia Using Unique Chitosan-PLGA Nanoparticles

2024-07-30

Abstract excerpt

<title>Abstract</title> <p>Introduction: Statins have pleiotropic effects, including reducing intimal hyperplasia (IH). Using unique nanoparticle (NPs), we hypothesized chitosan-functionalized polymeric NPs loaded with simvastatin (SL-cNPs) would: 1) readily associate with endothelial cells (ECs) and vascular smooth muscle cells (VSMCs); 2) affect EC and VSMC function; and 3) reduce IH compared to systemic simva...

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Literature Corpus work
694997e7-2083-5e42-8ebc-ee210387bbd3
DOI
10.21203/rs.3.rs-4601140/v1
Open publication

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Statin Targeted Treatment Against Intimal Hyperplasia Using Unique Chitosan-PLGA NanoparticlesDOI 10.21203/rs.3.rs-4601140/v1
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