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Article

Statins and Cardiovascular Diseases: From Cholesterol Lowering to Pleiotropy

30 Jan 2009

Abstract excerpt

Statins are 3-hydroxy-3-methyglutaryl coenzyme A (HMG-CoA) reductase inhibitors, which are prescribed extensively for cholesterol lowering in the primary and secondary prevention of cardiovascular disease. Recent compelling evidence suggests that the beneficial effects of statins may not only be due to their cholesterol lowering effects, but also, to their cholesterol-independent or pleiotropic effects. Through...

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PMID: 19199975
DOI: 10.2174/138161209787315684

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