Article

Mouse scalp development requires Rac1 and SRF for the maintenance of mechanosensing mesenchyme

2025-02-12

Abstract excerpt

<h4>ABSTRACT</h4> Regulation of essential cellular responses like proliferation, migration, and differentiation is crucial for normal development. Rac1, a ubiquitously expressed small GTPase, executes these responses under the regulation of guanine nucleotide exchange factors (GEFs) and GTPase activating proteins (GTPases). Mutations in specific GEFs (DOCK6) and GTPases (AHGAP31) that regulate Rac1 are associated...

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Literature Corpus work: 6930c1e6-3ed1-5195-a83c-17b13c173aec
DOI: 10.1101/2025.02.11.637680

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