Article

Novel mouse model of encephalocele: post-neurulation origin and relationship to open neural tube defects

2019-05-24

Abstract excerpt

<h4>ABSTRACT</h4> Encephalocele is a clinically important birth defect that can lead to severe disability in childhood and beyond. The embryonic pathogenesis of encephalocele is poorly understood and, while usually classified as a ‘neural tube defect’, there is conflicting evidence on whether encephalocele results from defective neural tube closure, or is a post-neurulation defect. It is also unclear whether ence...

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Literature Corpus work: 055421d5-bfd4-53a6-9a7e-5afa5566740c
DOI: 10.1101/649624

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