Article

Deep learning-guided selection of antibody therapies with enhanced resistance to current and prospective SARS-CoV-2 Omicron variants

2023-10-10

Abstract excerpt

<h4>ABSTRACT</h4> Most COVID-19 antibody therapies rely on binding the SARS-CoV-2 receptor binding domain (RBD). However, heavily mutated variants such as Omicron and its sublineages, which are characterized by an ever increasing number of mutations in the RBD, have rendered prior antibody therapies ineffective, leaving no clinically approved antibody treatments for SARS-CoV-2. Therefore, the capacity of therapeu...

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Literature Corpus work: 691a557b-0de1-5f06-90bf-0c39b8bfe58c
DOI: 10.1101/2023.10.09.561492

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