Article

Bitter Taste Signalling via TAS2R43 Enhances Temozolomide Efficacy in Glioblastoma Cells

2026-02-25

Abstract excerpt

Bitter taste receptors (TAS2Rs) are increasingly recognized as extraoral chemosensors that modulate diverse biological processes, including cancer cell behaviour and drug responsiveness. Many TAS2R ligands correspond to therapeutic compounds; however, their contribution to the response of brain tumours to chemotherapy remains unexplored. Here, we investigated whether the bitter taste signalling pathway is modulate...

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Literature Corpus work: 68eb5e79-f7aa-573e-ac9f-e695c4589495
DOI: 10.20944/preprints202602.1516.v1

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