Article

Pan-cancer analysis of the ion permeome reveals functional regulators of glioblastoma aggression

2023-04-08

Abstract excerpt

<h4>ABSTRACT</h4> Ion channels, transporters, and other ion-permeating proteins, collectively comprising the ion permeome (IP), are common drug targets. However, their roles in cancer are understudied. Our integrative pan-cancer analysis shows that IP genes display highly-elevated expression patterns in subsets of cancer samples significantly more often than expected transcriptome-wide. To enable target identific...

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Literature Corpus work: c56f581b-3133-5625-a80e-72476d702b7d
DOI: 10.1101/2023.04.07.536030

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