Ion Channel–Targeting Modulators in Glioma with Pharmacological Advances and Therapeutic Perspectives

Abstract excerpt

Despite advances in neurosurgery and oncology, many gliomas—particularly highly aggressive variants such as glioblastoma multiforme—remain exceedingly difficult to treat. While surgical resection can eliminate a considerable proportion of tumor mass, clinical outcomes are frequently compromised by tumor recurrence, increased invasiveness, metastatic spread, and the development of glioma-associated epilepsy. These...

Topics

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• Antineoplastic Agents
• Autophagy in Disease and Therapy
• Cardiac electrophysiology and arrhythmias
• Electrophysiological Phenomena
• Extracellular vesicles in disease
• Glioma Diagnosis and Treatment
• Ion channel regulation and function
• Nicotinic Acetylcholine Receptors Study

Identifiers and source

Literature Corpus work

dae59987-950c-5c99-a080-df4f18a32399

DOI

10.20944/preprints202606.1325.v1