Article

Strand Orientation Bias Detector (SOBDetector) to remove FFPE sequencing artifacts

2018-08-07

Abstract excerpt

<h4>ABSTRACT</h4> Formalin-fixed paraffin-embedded (FFPE) tissue, the most common tissue specimen stored in clinical practice, presents challenges in the analysis due to formalin-induced artifacts. Here we present SOBDetector, that is designed to remove these artifacts from a list of variants, which were extracted from next-generation sequencing data, using the posterior predictive distribution of a Bayesian logi...

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Literature Corpus work: 68c782e1-1823-5e61-85de-efb75495c4c4
DOI: 10.1101/386417

Open publication

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