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Article

Performance comparison of three DNA extraction kits on human whole-exome data from formalin-fixed paraffin-embedded normal and tumor samples.

PloS one - 1 Jan 2018

Bonnet Eric, Moutet Marie-Laure, Baulard Céline, Bacq-Daian Delphine, Sandron Florian, Mesrob Lilia, Fin Bertrand, Delépine Marc, Palomares Marie-Ange, Jubin Claire, Blanché Hélène, Meyer Vincent, Boland Anne, Olaso Robert, Deleuze Jean-François

Abstract excerpt

Next-generation sequencing (NGS) studies are becoming routinely used for the detection of novel and clinically actionable DNA variants at a pangenomic scale. Such analyses are now used in the clinical practice to enable precision medicine. Formalin-fixed paraffin-embedded (FFPE) tissues are still one of the most abundant source of cancer clinical specimen, unfortunately this method of preparation is known to...

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PMID: 29621323
DOI: 10.1371/journal.pone.0195471
PMCID: PMC5886566

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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