Article

An adaptive autoregressive diffusion approach to design active humanized antibody and nanobody

2024-10-25

Abstract excerpt

Humanization is a critical process for designing efficiently specific antibodies and nanobodies prior to clinical trials. Developing widely recognized deep learning techniques or frameworks for humanizing conventional antibodies and nanobodies presents a valuable yet challenging task. Inspired by the effectiveness of diffusion models across various applications, we introduce HuDiff, an adaptive diffusion approach...

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Literature Corpus work: effbaaaf-4da4-58b4-9e42-ea7c887ee055
DOI: 10.1101/2024.10.22.619416

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