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Article

Homeostatic plasticity in the retina is associated with maintenance of night vision during retinal degenerative disease.

eLife - 22 Sept 2020

Leinonen Henri, Pham Nguyen C, Boyd Taylor, Santoso Johanes, Palczewski Krzysztof, Vinberg Frans

Abstract excerpt

Neuronal plasticity of the inner retina has been observed in response to photoreceptor degeneration. Typically, this phenomenon has been considered maladaptive and may preclude vision restoration in the blind. However, several recent studies utilizing triggered photoreceptor ablation have shown adaptive responses in bipolar cells expected to support normal vision. Whether such homeostatic plasticity occurs during...

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Identifiers

PMID: 32960171
DOI: 10.7554/eLife.59422
PMCID: PMC7529457

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