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Pathways and disease-causing alterations in visual chromophore production for vertebrate vision

13 Nov 2020

Abstract excerpt

All that we view of the world begins with an ultrafast cis to trans photoisomerization of the retinylidene chromophore associated with the visual pigments of rod and cone photoreceptors. The continual responsiveness of these photoreceptors is then sustained by regeneration processes that convert the trans-retinoid back to an 11-cis configuration. Recent biochemical and electrophysiological analyses of the retinal...

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PMID: 33187985
DOI: 10.1074/jbc.rev120.014405

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