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Spatial Dynamics Links PD-L1 and Tumor-Associated Macrophage–Enriched Niches to Immune and Mesenchymal States in Microsatellite Stable Colorectal Cancer

2026-03-11

Abstract excerpt

<h4>Background: </h4> /Objectives: MSS-CRC comprises a heterogeneous group of tumors generally considered “immune cold” due to limited neoantigen generation and T-cell exclusion or inactivation. Current evidence indicates that the composition of T and B immune cells within the tumor microenvironment represents a prognostically relevant factor, significantly associated with both tumor expression profiles and molecu...

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Literature Corpus work
5fda08d5-97d7-5476-bae9-fc8146574e40
DOI
10.20944/preprints202603.0869.v1
Open publication

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Spatial Dynamics Links PD-L1 and Tumor-Associated Macrophage–Enriched Niches to Immune and Mesenchymal States in Microsatellite Stable Colorectal CancerDOI 10.20944/preprints202603.0869.v1
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