Article

Peripheral immune profiles in individuals at genetic risk for amyotrophic lateral sclerosis and Alzheimer’s disease

2024-11-13

Abstract excerpt

The immune system plays a crucial role in the pathogenesis of neurodegenerative diseases. Here, we explored whether blood immune cell profiles are already altered in healthy individuals with a genetic predisposition to amyotrophic lateral sclerosis (ALS) or Alzheimer’s disease (AD). Using multicolor flow cytometry, we analyzed 92 immune cell phenotypes in the blood of 448 healthy participants from the Berlin Aging...

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Literature Corpus work: 683b1f5e-9fcf-5afb-9863-0c14a895d9f7
DOI: 10.1101/2024.11.13.24316906

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