Article

Immune cell distributions in the blood of healthy individuals at high genetic risk of Parkinson’s disease

2024-11-02

Abstract excerpt

The immune system likely plays a key role in Parkinson’s disease (PD) pathophysiology. Thus, we investigated whether immune cell compositions are already altered in healthy individuals at high genetic risk for PD. We quantified 92 immune cell subtypes in the blood of 442 individuals using multicolor flow cytometry. Polygenic risk scores (PGS) for PD were calculated based on genome-wide significant SNPs (n = 87) fr...

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Literature Corpus work: 16a39b57-aeb4-559a-bce2-2f08b2c4d8f5
DOI: 10.1101/2024.10.31.24316489

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