Article

Optimized Quantification of Intrahost Viral Diversity in SARS-CoV-2 and Influenza Virus Sequence Data

2021-05-06

Abstract excerpt

<h4>ABSTRACT</h4> High error rates of viral RNA-dependent RNA polymerases lead to diverse intra-host viral populations during infection. Errors made during replication that are not strongly deleterious to the virus can lead to the generation of minority variants. However, accurate detection of minority variants in viral sequence data is complicated by errors introduced during sample preparation and data analysis....

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Literature Corpus work: 6837d616-3106-5fd7-b3e3-7d3242951f83
DOI: 10.1101/2021.05.05.442873

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