Article

Intra-host site-specific polymorphisms of SARS-CoV-2 is consistent across multiple samples and methodologies

2020-04-29

Abstract excerpt

<h4>ABSTRACT</h4> Despite the potential relevance to clinical outcome, intra-host dynamics of SARS-CoV-2 are unclear. Here, we quantify and characterize intra-host variation in SARS-CoV-2 raw sequence data uploaded to SRA as of 14 April 2020, and compare results between two sequencing methods (amplicon and RNA-Seq). Raw fastq files were quality filtered and trimmed using Trimmomatic, mapped to the WuhanHu1 referen...

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Literature Corpus work: 1c9f9e89-8d31-58ab-9b73-a29c4bbbcad5
DOI: 10.1101/2020.04.24.20078691

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