Article

SIGNET: Transcriptome-wide Causal Inference for Gene Regulatory Networks

2023-07-26

Abstract excerpt

Gene regulation plays an important role in understanding the mechanisms of human biology and diseases. However, inferring causal relationships between all genes is challenging due to the large number of genes in the transcriptome. Here, we present SIGNET (Statistical Inference on Gene Regulatory Networks), a flexible software package that reveals networks of causal regulation between genes built upon large-scale t...

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Literature Corpus work: 6830044f-19b3-59ef-b08f-64cf9430f399
DOI: 10.21203/rs.3.rs-3180043/v1

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