Article

NUP98/NSD1 and FLT3/ITD co-expression is an independent predictor of poor prognosis in pediatric AML patients.

2024-05-10

Abstract excerpt

<title>Abstract</title> <p>Objective Patients who carry NUP98/NSD1 or FLT3/ITD mutations are reported to have poor prognosis. Previous studies have confidently reported that the poor outcome in younger AML patients is owning to dual NUP98/NSD1 positivity and FLT3/ITD positivity, with a high overlap for those two genetic lesions. In this study, we assessed the prognostic value of the presence of both NUP98/NSD1 a...

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Literature Corpus work: 68178b19-a3a6-563b-8176-27b6142aafc4
DOI: 10.21203/rs.3.rs-4116044/v1

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