Article

Genetic variants of MUC4 are associated with prevalence and mortality of colorectal cancer and exhibit synergistic effects with LDL-C levels

2022-09-12

Abstract excerpt

As a disease with high mortality and prevalence rates worldwide, colorectal cancer (CRC) has been thoroughly investigated. Mucins are involved in the induction of CRC and regulation of intestinal homeostasis. However, the role of MUC4, which is a member of the mucin gene family, is controversial because it shows an association with either decreased susceptibility to or a worse prognosis of CRC. In our study, the m...

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Literature Corpus work: 6815cb61-f736-57bb-8fbc-a9dae761dec3
DOI: 10.21203/rs.3.rs-2040638/v1

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