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A higher dietary alpha-linolenic acid intake is associated with lower colorectal cancer risk based on MUC4 rs2246901 variant among Korean adults.

Nutrition research (New York, N.Y.) - 1 Nov 2024

Nguyen Ha Thi Mien, Gunathilake Madhawa, Lee Jeonghee, Oh Jae Hwan, Chang Hee Jin, Sohn Dae Kyung, Shin Aesun, Kim Jeongseon

Abstract excerpt

Alpha-linolenic acid (C18:3n-3 [ALA]) intake may have a beneficial effect in reducing cancer risk; however, its association with colorectal cancer (CRC) risk remains conflicted. Additionally, ALA was emphasized as being associated with mucins, an important glycoproteins family within the intestine. Thus, we hypothesized that a higher dietary ALA intake may reduce the risk of CRC and this preventive effect has an...

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PMID: 39369551
DOI: 10.1016/j.nutres.2024.09.003

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MUC4

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