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Article

Genetic variants in MUC4 gene are associated with lung cancer risk in a Chinese population.

PloS one - 1 Jan 2013

Zhang Zili, Wang Jian, He Jianxing, Zheng Zeguang, Zeng Xiansheng, Zhang Chenting, Ye Jinmei, Zhang Yajie, Zhong Nanshan, Lu Wenju

Abstract excerpt

Mucin MUC4, which is encoded by the MUC4 gene, plays an important role in epithelial cell proliferation and differentiation. Aberrant MUC4 overexpression is associated with invasive tumor proliferation and poor outcome in epithelial cancers. Collectively, the existing evidence suggests that MUC4 has tumor-promoter functions. In this study, we performed a case-control study of 1,048 incident lung cancer cases and...

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Identifiers

PMID: 24204934
DOI: 10.1371/journal.pone.0077723
PMCID: PMC3804582

Genes

MUC4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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