Functional polymorphism rs4072037 in MUC1 gene contributes to the susceptibility to gastric cancer: evidence from pooled 6,580 cases and 10,324 controls.

doi:10.1007/s11033-013-2682-4

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Functional polymorphism rs4072037 in MUC1 gene contributes to the susceptibility to gastric cancer: evidence from pooled 6,580 cases and 10,324 controls.

Molecular biology reports - 1 Oct 2013

Zheng Leizhen, Zhu Chen, Gu Jianchun, Xi Pan, Du Jiangbo, Jin Guangfu

Abstract excerpt

Genome-wide association studies have reported a promising association of rs4072037 with gastric cancer (GC). This variant was associated with altered physiological function of MUC1 possibly by modulating promoter activity and alternative splicing of MUC1. However, the association results were inconclusive and estimate of the effect of this variant was not well evaluated. A meta-analysis by systematically...

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PMID: 24072653
DOI: 10.1007/s11033-013-2682-4

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MUC1

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