Article

Mechanistic Deep Learning Framework on Cell Traits Derived from Single-Cell Mass Cytometry Data

2022-08-29

Abstract excerpt

Germline genetic variations can alter cellular differentiation, potentially impacting the response of immune cells to inflammatory challenges. Current variant- and gene-based methods in mouse and human models have established associations with disease phenotypes; however, the underlying mechanisms at the cellular level are less well-understood. Immunophenotyping by multi-parameter flow cytometry, and more recently...

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Literature Corpus work: 884974a0-5c22-592f-a6b9-0c3949a8a1e3
DOI: 10.1101/2022.08.22.504669

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