Article

Methylation pattern of polymorphically imprinted <i>nc886</i> is not conserved across mammalia

2021-12-03

Abstract excerpt

<h4>Background</h4> In humans, the nc886 locus is a polymorphically imprinted metastable epiallele. Periconceptional conditions have an effect on the methylation status of nc886 , and further, this methylation status is associated with health outcomes in later life, in line with the Developmental Origins of Health and Disease (DOHaD) hypothesis. Animal models would offer opportunities to study the associations...

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Literature Corpus work: 67e72ca8-62f3-5b51-8fee-2a7db52935d1
DOI: 10.1101/2021.12.03.471165

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