Article

Genetic and acquired abnormalities in C3 glomerulopathy and primary immune complex-mediated MPGN

2018-01-01

Abstract excerpt

Membranoproliferative glomerulonephritis (MPGN) is an uncommon cause of glomerular injury that mainly occurs in children and young adults. MPGN is currently classified in immune complex-mediated MPGN (IC-MPGN), characterized by activation of the complement classic pathway, and C3 Glomerulopathy (C3G), with predominant complement alternative pathway (AP) activation. C3G is further classified in Dense Deposit Diseas...

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Literature Corpus work: 6783d87d-e2a6-508a-8167-32059b99a7f0
DOI: 10.21954/ou.ro.0000da2c

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