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Membranoproliferative glomerulonephritis: no longer the same disease and may need very different treatment

30 Sept 2021

Abstract excerpt

Membranoproliferative glomerulonephritis (MPGN) is a pattern of glomerular injury that may be primary or secondary to infections, autoimmune diseases and haematological disorders. Primary C3G and IC-MPGN are rare and the prognosis is unfavourable. Based on immunofluorescence findings, MPGN has been classified into complement-mediated C3 glomerulopathy (C3G) and immune complex-mediated MPGN (IC-MPGN). However,...

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PMID: 34596686
DOI: 10.1093/ndt/gfab281

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