Article

Integrating simulated and experimental data to identify mitochondrial bioenergetic defects in Parkinson’s Disease models

2025-05-03

Abstract excerpt

Mitochondrial bioenergetics are vital for ATP production and are associated with several diseases, including Parkinson’s Disease. Here, we simulated a computational model of mitochondrial ATP production to interrogate mitochondrial bioenergetics under physiological and pathophysiological conditions, and provide a data resource that can be used to interpret mitochondrial bioenergetics experiments. We first characte...

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Identifiers and source

Literature Corpus work: 6781d234-a6d6-5316-a82c-558a1dad1c48
DOI: 10.1101/2025.04.29.651221

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