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Article

Bioenergetic origins of complexity and disease.

Cold Spring Harbor symposia on quantitative biology - 1 Jan 2011

Wallace D C

Abstract excerpt

The organizing power of energy flow is hypothesized to be the origin of biological complexity and its decline the basis of "complex" diseases and aging. Energy flow through organic systems creates nucleic acids, which store information, and the annual accumulation of information generates today's complexity. Energy flow through our bodies is mediated by the mitochondria, symbiotic bacteria whose genomes encompass...

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Identifiers

PMID: 22194359
DOI: 10.1101/sqb.2011.76.010462
PMCID: PMC4405153

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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