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Article

PTEN Loss Correlates with T cell Exclusion across Human Cancers

2021-05-18

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Recent evidences had shown that loss in phosphatase and tensin homolog deleted on chromosome 10 (PTEN) was associated with immunotherapy resistance, which may be attributed to the non-T-cell-inflamed tumor microenvironment. The impact of PTEN loss on tumor microenvironment, especially regarding T cell infiltration across tumor types is not well understood.<bold>...

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Literature Corpus work
6772cb6a-e28c-5bd6-965b-32289a03096a
DOI
10.21203/rs.3.rs-531066/v1
Open publication

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PTEN Loss Correlates with T cell Exclusion across Human CancersDOI 10.21203/rs.3.rs-531066/v1
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