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Immune Landscape in PTEN-Related Glioma Microenvironment: A Bioinformatic Analysis

14 Apr 2022

Abstract excerpt

Introduction: PTEN gene mutations are frequently found in the genetic landscape of high-grade gliomas since they influence cell proliferation, proangiogenetic pathways, and antitumoral immune response. The present bioinformatics analysis explores the PTEN gene expression profile in HGGs as a prognostic factor for survival, especially focusing on the related immune microenvironment. The effects of PTEN mutation on...

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PMID: 35448032
DOI: 10.3390/brainsci12040501

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