Article

Intergenerational control of ribosomes under dietary restriction

2025-03-07

Abstract excerpt

Cells adjust their proteome to their environment. Most prominently, ribosome expression scales near linearly with the cellular growth rate to provide sufficient translational capacity while preventing metabolically wasteful ribosomal excess. In microbes, such proteome adjustments can passively perpetuate through symmetric cell division. However, in animals, a passive propagation is hindered by the separation betwe...

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Literature Corpus work: 676396be-2f7d-5ea2-8f54-fb04f6722b8e
DOI: 10.1101/2025.03.01.640961

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