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Adaptation-proof SARS-CoV-2 vaccine design

2022-05-18

Abstract excerpt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) surface spike glycoprotein - a major antibody target - is critical for virus entry via engagement of human angiotensin-converting enzyme 2 (ACE2) receptor. Despite successes with existing vaccines and therapies that primarily target the receptor binding domain (RBD) of the spike protein, the susceptibility of RBD to mutations provides escape routes for t...

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Literature Corpus work
675f07da-3197-53cc-b653-5146a4ade8ab
DOI
10.1101/2022.05.17.492310
Open publication

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Adaptation-proof SARS-CoV-2 vaccine designDOI 10.1101/2022.05.17.492310
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