Article

Spike Proteins of SARS –CoV-2: a detailed perspective on structure, receptor binding, antigenicity, vaccine development and neutralization

2024-01-31

Abstract excerpt

Spike proteins are heavily glycosylated, small protrusions located on the envelops of coronavirus. These proteins are the characteristic morphological features of coronavirus that give the virus family its name, and are alone responsible for the virulence, pathogenicity, and evolving tropism of these viruses. SARS-CoV-2 shows higher affinity towards its target, ACE-2 receptors in human subjects. This affinity is t...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a7a3a9f4-284d-5459-8aa7-5c1ac9c325da
DOI: 10.22541/au.170668860.08515933/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Spike Proteins of SARS –CoV-2: a detailed perspective on structure, receptor binding, antigenicity, vaccine development and neutralizationDOI 10.22541/au.170668860.08515933/v1Read

The SARS-CoV-2 Spike Glycoprotein Biosynthesis, Structure, Function, and Antigenicity: Implications for the Design of Spike-Based Vaccine ImmunogensSemantic proximity Read

What makes SARS‐CoV‐2 unique? Focusing on the spike proteinSemantic proximity Read

The SARS-CoV-2 Spike Glycoprotein as a Drug and Vaccine Target: Structural Insights into Its Complexes with ACE2 and AntibodiesSemantic proximity Read

Up, up, down, down: the structural biology of the SARS-CoV-2 spike protein and how it cheats the immune systemSemantic proximity Read

Architects of infection: A structural overview of SARS-related coronavirus spike glycoproteinsSemantic proximity Read

Spike protein of SARS-CoV-2 variants: a brief review and practical implications.Semantic proximity Read

Severe Acute Respiratory Syndrome Coronavirus 2 Variants of Concern: A Perspective for Emerging more Transmissible and Vaccine-Resistant StrainsSemantic proximity Read

Significance of Conserved Regions in Coronavirus Spike Protein for Developing a Novel Vaccine against SARS-Cov-2 InfectionSemantic proximity Read

Significance of Conserved Regions in Coronavirus Spike Protein for Developing a Novel Vaccine against SARS-CoV-2 InfectionSemantic proximity Read

Severe Acute Respiratory Syndrome Coronavirus 2 Variants of Concern: A Perspective for Emerging More Transmissible and Vaccine-Resistant Strains.Semantic proximity Read

A Comprehensive Analysis of Structural and Functional Changes Induced by SARS-CoV-2 Spike Protein MutationsSemantic proximity Read

SARS-CoV-2 journey: from alpha variant to omicron and its sub-variants.Semantic proximity Read