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Article

Rapid identification of neutralizing antibodies against SARS-CoV-2 variants by mRNA display

19 Jan 2022

Abstract excerpt

The increasing prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with the ability to escape existing humoral protection conferred by previous infection and/or immunization necessitates the discovery of broadly reactive neutralizing antibodies (nAbs). Utilizing mRNA display, we identify a set of antibodies against SARS-CoV-2 spike (S) proteins and characterize the structures of...

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PMID: 35114110
DOI: 10.1016/j.celrep.2022.110348

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