Article

The Potential for SARS-CoV-2 to Evade Both Natural and Vaccine-induced Immunity

2020-12-13

Abstract excerpt

SARS-CoV-2 attaches to the surface of susceptible cells through extensive interactions between the receptor binding domain (RBD) of its spike protein and angiotensin converting enzyme type 2 (ACE2) anchored in cell membranes. To investigate whether naturally occurring mutations in the spike protein are able to prevent antibody binding, yet while maintaining the ability to bind ACE2 and viral infectivity, mutations...

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Literature Corpus work: c558b13d-9d1a-5d60-a9a8-cd9f4cfe3ad1
DOI: 10.1101/2020.12.13.422567

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