Article

Somatic structural variants driving distinct modes of oncogenesis in melanoma

2023-11-04

Abstract excerpt

The diversity of structural variants (SVs) in melanoma and how they impact oncogenesis are incompletely known. We performed harmonized analysis of SVs across melanoma histological and genomic subtypes, and we identified distinct global properties between subtypes. These included the frequency and size of SVs and SV classes, their relation to chromothripsis events, and the role of topologically associated domain (T...

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Literature Corpus work: 675075af-40af-5042-a0e4-923a5bf2b3f0
DOI: 10.1101/2023.11.01.565187

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