Article
Comparative Genomics Provides Etiologic and Biological Insight into Melanoma Subtypes.
Cancer discovery - 2 Dec 2022
Newell Felicity, Johansson Peter A, Wilmott James S, Nones Katia, Lakis Vanessa, Pritchard Antonia L, Lo Serigne N, Rawson Robert V, Kazakoff Stephen H, Colebatch Andrew J, Koufariotis Lambros T, Ferguson Peter M, Wood Scott, Leonard Conrad, Law Matthew H, Brooks Kelly M, Broit Natasa, Palmer Jane M, Couts Kasey L, Vergara Ismael A, Long Georgina V, Barbour Andrew P, Nieweg Omgo E, Shivalingam Brindha, Robinson William A, Stretch Jonathan R, Spillane Andrew J, Saw Robyn P M, Shannon Kerwin F, Thompson John F, Mann Graham J, Pearson John V, Scolyer Richard A, Waddell Nicola, Hayward Nicholas K
Abstract excerpt
Melanoma is a cancer of melanocytes, with multiple subtypes based on body site location. Cutaneous melanoma is associated with skin exposed to ultraviolet radiation; uveal melanoma occurs in the eyes; mucosal melanoma occurs in internal mucous membranes; and acral melanoma occurs on the palms, soles, and nail beds. Here, we present the largest whole-genome sequencing study of melanoma to date, with 570 tumors...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.