Article

Blood-derived mitochondrial DNA copy number is associated with gene expression across multiple tissues and is predictive for incident neurodegenerative disease

2020-07-18

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Mitochondrial DNA copy number (mtDNA-CN) can be used as a proxy for mitochondrial function and is associated with a number of aging-related diseases. However, it is unclear how mtDNA-CN measured in blood can reflect risk for diseases that primarily manifest in other tissues. Using the Genotype-Tissue Expression Project, we interrogated the relationships between mtDNA-CN meas...

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Literature Corpus work: 672fc626-c48c-5bf1-9d26-b29c08f341d1
DOI: 10.1101/2020.07.17.209023

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