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The Role of Mitochondrial Copy Number in Neurodegenerative Diseases: Present Insights and Future Directions

31 May 2024

Abstract excerpt

Neurodegenerative diseases are progressive disorders that affect the central nervous system (CNS) and represent the major cause of premature death in the elderly. One of the possible determinants of neurodegeneration is the change in mitochondrial function and content. Altered levels of mitochondrial DNA copy number (mtDNA-CN) in biological fluids have been reported during both the early stages and progression of...

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PMID: 38892250
DOI: 10.3390/ijms25116062

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