Article

Snail maintains the stem/progenitor state of skin epithelial cells and carcinomas through the autocrine effect of the matricellular protein Mindin

2021-06-29

Abstract excerpt

<h4>Summary</h4> Intratumoral heterogeneity poses a major challenge in designing effective anti-cancer strategies. Accumulating evidence suggests that this heterogeneity arises from cancer stem cells (CSCs) that also drives tumor aggressiveness and drug resistance. The stemness of CSCs are preserved by an ill-defined combination of intrinsic and external factors and is particularly intriguing since they exist wit...

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Literature Corpus work: 672b700f-2a29-586d-b2f0-3f99f259c8ff
DOI: 10.1101/2021.06.26.450022

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