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Basal cell carcinoma: cell of origin, cancer stem cell hypothesis and stem cell markers

3 Dec 2010

Abstract excerpt

Cancer stem cells have recently been described in several high-grade neoplasms. It is still unclear if they also occur in cutaneous malignancies. Cancer stem cells are not identical with somatic stem cells. The presence of tumour stem cells in a neoplasm does not in itself equal that the tumour derives from a somatic stem cell. A cell originally lacking stem cell characteristics could also acquire those features...

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PMID: 21128907
DOI: 10.1111/j.1365-2133.2010.10158.x

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