Article

miR-184 represses β-catenin and behaves as a skin tumor suppressor

2023-09-20

Abstract excerpt

<title>Abstract</title> <p>miR-184-knockout mice display perturbed epidermal stem cell differentiation. However, the potential role of miR-184 in skin pathology is unclear. Here, we report that miR-184 controls epidermal stem cell dynamics and that miR-184 ablation enhances skin carcinogenesis in mice. In agreement, repression of miR-184 in human squamous cell carcinoma (SCC) enhances neoplastic hallmarks of huma...

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Literature Corpus work: ba48b49d-f27a-564d-81cc-eeef2cfcb0aa
DOI: 10.21203/rs.3.rs-3216354/v1

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