Article

Molecular evolution and diversity of isomerase–reductase operons involved in bacterial metabolism of glycosaminoglycans

2025-01-30

Abstract excerpt

<h4>ABSTRACT</h4> Glycosaminoglycans (GAGs), comprising uronic acids and amino sugars, are widely distributed in human tissues such as the intestine and oral cavity. Various bacteria colonize these tissues by assimilating GAGs. 4-Deoxy-L- threo -5-hexosulose uronate (DHU) is produced during the degradation of GAGs. Pectin, abundant in plants, is also degraded into DHU. DHU is metabolized in a stepwise manner by...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6709c30e-03ab-5577-9a39-eda6c2dc3714
DOI: 10.1101/2025.01.30.635655

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Molecular evolution and diversity of isomerase–reductase operons involved in bacterial metabolism of glycosaminoglycansDOI 10.1101/2025.01.30.635655Read

UDP-hexose 4-epimerases: a view on structure, mechanism and substrate specificity.Semantic proximity Read

A reductive uric acid degradation pathway in anaerobic bacteriaSemantic proximity Read

The presence and induction of regioselective dehydroxylases dictate urolithin metabolism by <i>Enterocloster</i> speciesSemantic proximity Read

Biology, Mechanism, and Structure of Enzymes in the α-d-Phosphohexomutase Superfamily.Semantic proximity Read

A Reductive Uric Acid Degradation Pathway in Anaerobic BacteriaSemantic proximity Read

Characterization of l-2-keto-3-deoxyfuconate aldolases in a nonphosphorylating l-fucose metabolism pathway in anaerobic bacteria.Semantic proximity Read

Human Milk Oligosaccharide Utilization in Intestinal Bifidobacteria is Governed by a Global Transcriptional Regulator NagRSemantic proximity Read

Phylogenetic analyses suggest multiple changes of substrate specificity within the Glycosyl hydrolase 20 familySemantic proximity Read

Streptococcal phosphotransferase system imports unsaturated hyaluronan disaccharide derived from host extracellular matricesSemantic proximity Read

Genetic Characterization of Glyoxalase Pathway in Oral Streptococci and its Contribution to Interbacterial CompetitionSemantic proximity Read

Determinants of raffinose family oligosaccharide use in <i>Bacteroides</i> speciesSemantic proximity Read

Discovery of α-l-arabinopyranosidases from human gut microbiome expands the diversity within glycoside hydrolase family 42.Semantic proximity Read