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Article

UDP-hexose 4-epimerases: a view on structure, mechanism and substrate specificity.

Carbohydrate research - 23 Sept 2015

Beerens Koen, Soetaert Wim, Desmet Tom

Abstract excerpt

UDP-sugar 4-epimerase (GalE) belongs to the short-chain dehydrogenase/reductase (SDR) superfamily of proteins and is one of enzymes in the Leloir pathway. They have been shown to be important virulence factors in a number of Gram-negative pathogens and to be involved in the biosynthesis of different polysaccharide structures. The metabolic disease type III galactosemia is caused by detrimental mutations in the...

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Source

Identifiers

PMID: 26162744
DOI: 10.1016/j.carres.2015.06.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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