Article
Discovery of α-l-arabinopyranosidases from human gut microbiome expands the diversity within glycoside hydrolase family 42.
The Journal of biological chemistry - 22 Dec 2017
Viborg Alexander Holm, Katayama Takane, Arakawa Takatoshi, Abou Hachem Maher, Lo Leggio Leila, Kitaoka Motomitsu, Svensson Birte, Fushinobu Shinya
Abstract excerpt
Enzymes of the glycoside hydrolase family 42 (GH42) are widespread in bacteria of the human gut microbiome and play fundamental roles in the decomposition of both milk and plant oligosaccharides. All GH42 enzymes characterized so far have β-galactosidase activity. Here, we report the existence of a GH42 subfamily that is exclusively specific for α-l-arabinopyranoside and describe the first representative of this...
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