Article

Human Milk Oligosaccharide Utilization in Intestinal Bifidobacteria is Governed by a Global Transcriptional Regulator NagR

2022-04-07

Abstract excerpt

Bifidobacterium longum subsp. infantis ( B. infantis ) is a prevalent beneficial bacterium that colonizes the human neonatal gut and is uniquely adapted to efficiently use human milk oligosaccharides (HMOs) as a carbon and energy source. Multiple studies have focused on characterizing the elements of HMO utilization machinery in B. infantis ; however, the regulatory mechanisms governing the expression of these...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c26d2eb6-d09d-55f6-9930-108c1f487547
DOI: 10.1101/2022.04.06.487429

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Human Milk Oligosaccharide Utilization in Intestinal Bifidobacteria is Governed by a Global Transcriptional Regulator NagRDOI 10.1101/2022.04.06.487429Read

Identification of a novel Human Milk Oligosaccharides utilization cluster in the infant gut commensal Bacteroides doreiSemantic proximity Read

A bifidobacterial enzyme orchestrates ecology and function of infant gut bacterial communitySemantic proximity Read

Milk glycan metabolism by intestinal bifidobacteria: insights from comparative genomicsSemantic proximity Read

Metabolism of the predominant human milk oligosaccharide fucosyllactose by an infant gut commensalSemantic proximity Read

Elucidating Human Milk Oligosaccharide biosynthetic genes through network-based multiomics integrationSemantic proximity Read

Mutualistic interactions between Escherichia coli and Bifidobacterium bifidum enable degradation of human milk oligosaccharides in healthy infantsSemantic proximity Read

Bifidobacterium breve UCC2003 metabolises the human milk oligosaccharides lacto-N-tetraose and lacto-N-neo-tetraose through overlapping, yet distinct pathways.Semantic proximity Read

Breast milk-derived human milk oligosaccharides promote Bifidobacterium interactions within a single ecosystem.Semantic proximity Read

In silico analysis of the human milk oligosaccharide glycome reveals key enzymes of their biosynthesisSemantic proximity Read

Human milk oligosaccharide metabolism and antibiotic resistance in early gut colonizers: insights from bifidobacteria and lactobacilli in the maternal-infant microbiomeSemantic proximity Read

Linking human milk oligosaccharide metabolism and early life gut microbiota: bifidobacteria and beyondSemantic proximity Read

Targeted High-Resolution Taxonomic Identification of <i>Bifidobacterium longum</i> subsp. <i>infantis</i> Using Human Milk Oligosaccharide Metabolizing GenesSemantic proximity Read