Article

Modeling immunoglobulin light chain amyloidosis in Caenorhabditis elegans

2024-10-08

Abstract excerpt

<title>Abstract</title> <p>Cardiomyopathy determines the prognosis of patients with immunoglobulin light chain (AL) amyloidosis, a rare systemic disease caused by the misfolding and deposition of monoclonal light chains (LCs). The reasons underlining their cardiac tropism remain unknown, and an animal model recapitulating the main pathological features of AL amyloidosis is instrumental. Taking advantage of the si...

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Literature Corpus work: 66ecb7c3-1dce-56ef-aa61-04225304a254
DOI: 10.21203/rs.3.rs-4848043/v1

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